KPV
Alpha-MSH 11-13 fragment
The file here is mostly preclinical work plus clinic and community practice, not registrational trials.
Studied mostly in colitis models for anti-inflammatory signalling without the pigmentation effects of full alpha-MSH.
General profile
- Class
- Healing and tissue
- Evidence
- Early or preclinical only
- Studied dose range
- 200–500 mcg
- Frequency in protocols
- Daily
- Route
- Subcutaneous or oral in gut studies
- Half life
- Short
- Reconstitution
- 2 mL bacteriostatic water per 5 mg vial
- Storage
- Refrigerated, ~30 days
Timing and cycling in the literature
Usually dosed in the evening window
Daily
Anti-inflammatory signalling studied in gut models with daily dosing. Time of day is not a documented variable.
Reported cycle: 4 weeks on, 2 weeks off
Studied for flare control in gut inflammation models, which is a short course problem.
Watch for: Injection site reactions and any change in gut symptoms.
What it conflicts with
Three separate questions, kept separate. A hard stop means the mechanisms must not run together at all and timing does not fix it. A syringe rule means the same day is fine but one barrel is not. Redundancy is not dangerous, it is paying twice to hit one target.
- Pick oneRedundant, pick one
KPV + KLOW (GLOW + KPV)
Same target hit twice
KLOW already carries KPV.
Most syringe compatibility claims here are practice and expert consensus, not peer reviewed mixing studies. A clear liquid after mixing does not prove the compounds are still active, and cloudiness, particles or gelling means discard. Active cancer, pregnancy, major cardiac care and heavy immunosuppression override every stack preference on this page.
See how KPV fits your week
The injection scheduler spaces doses using the clinical timing data, flags the pairs above before you draw them, and tells you why.
Model this in the injection schedulerThe studies
Human trials: No completed human efficacy trial that establishes a dose for the use people are chasing.
Open questions: Treat published dosing as observed practice, not a validated protocol.
Published papers
Indexed from Europe PMC and refreshed weekly. Each link opens the paper itself.
- Influence of Water Source Quality on Concrete Performance: A Mechanism-Based Systematic Review and Engineering Evaluation Framework
Materials (Basel) · 2026 · Review. Robles KPV, Cordova JN, Kinazo MC, Kee SH.
- Subspecies Identification and Characterization of Drug Resistance and Virulence Factors in Clinical Strains of <i>Mycobacterium abscessus</i> Complex Isolated from South India
Infect Dis Rep · 2026. Oudhaya K, Kalaiarasan E, Alex A, Hyma KPV, Padmanaban H, Jayagandan S, Joseph NM.
- Exploration of 1,3,4-Thiadiazole Bearing Quinolin-2(1H)-One Hybrids as Potent Antimycobacterial Agents: Design, Synthesis, and In Silico Docking Techniques
Curr Org Synth · 2026. Mangali RSK, Nanda KPVV, Bhoomandla S, Sanaboyina DN.
- A new era of doping? Use of peptide and peptide-analog drugs in recreational and professional sport and bodybuilding: a critical review
J Sports Med Phys Fitness · 2026 · Review. Coutinho LFD, DE Oliveira Neves LF, Camilo RP.
- Pediatric Neuroinflammatory and Neuropsychiatric Syndromes Associated with Dupilumab Treatment for Atopic Dermatitis
J Pediatr · 2026. Mathiesen L, Santoro JD, Lee NJ, van Haren KP.
- Lysine-proline-valine peptide attenuates hepatic lipid accumulation through ROS-dependent regulation of the PPARγ pathway in HepG2 cells
Cytotechnology · 2026. Lee JY, Lee J, Jung WK, Je JY, Lee SJ.
- Spatial variability of soil attributes and risk of phosphorus loss in different soil classes of the Potengi River Basin, Brazil
Environ Monit Assess · 2026. Ramalho JADN, da Cunha KPV, de Sousa MNFA, Pereira CVM, de Medeiros LF, Costa CW.
- Living Hydrogels: Harnessing Microorganism-Material Synergy for Next-Generation Therapeutics
Adv Sci (Weinh) · 2026 · Review. Mao S, Bai B, Ye X, Lin Y.
- Therapeutic Peptides in Aesthetic, Metabolic and Endocrine Conditions: Effects, Safety, Clinical Applications, and Future Perspectives
Int J Mol Sci · 2026 · Review. Renke G, Chinellato L.
- Chronic Wound Healing: Research Advances from Pathological Mechanisms to Natural Herbal Active Ingredients and Material Delivery Systems
Molecules · 2026 · Review. Yuan M, Liu Y, Peng X, Li Z, Lei M.
Search the full literature
- PubMed: all indexed papers
Every indexed paper, newest first. Filter to Clinical Trial or Review in the sidebar.
- PubMed: human clinical trials only
The honest test of an evidence claim. An empty result is itself an answer.
- ClinicalTrials.gov registrations
Registered, ongoing and completed trials, including ones that never published.
- Europe PMC full text
Often surfaces open-access full text that PubMed only abstracts.