
DSIP
Delta sleep-inducing peptide
The file here is mostly preclinical work plus clinic and community practice, not registrational trials.
General profile
- Class
- Cognitive
- Evidence
- Early or preclinical only
- Studied dose range
- 100–200 mcg
- Frequency in protocols
- Nightly
- Route
- Subcutaneous
- Half life
- ~7 minutes (effect outlasts plasma)
- Reconstitution
- 2 mL bacteriostatic water per 5 mg vial
- Storage
- Refrigerated, ~30 days
Timing and cycling in the literature
Usually dosed in the bedtime window
Nightly
The entire mechanism of interest is sleep architecture. Dosing outside the pre-sleep window makes no sense.
Reported cycle: 4 weeks on, 2 weeks off
Sleep protocols are short because the goal is to reset a pattern, not to depend on an injection to sleep.
Watch for: Morning grogginess and vivid dreams. Track sleep objectively rather than by feel.
What it conflicts with
Three separate questions, kept separate. A hard stop means the mechanisms must not run together at all and timing does not fix it. A syringe rule means the same day is fine but one barrel is not. Redundancy is not dangerous, it is paying twice to hit one target.
- Separate syringesTiming
DSIP + Semax
Opposite ends of the day, minimum 8 hours
One is studied for sedation and slow-wave sleep, the other for alertness. Co-administering them cancels the observable effect of both and tells you nothing.
Most syringe compatibility claims here are practice and expert consensus, not peer reviewed mixing studies. A clear liquid after mixing does not prove the compounds are still active, and cloudiness, particles or gelling means discard. Active cancer, pregnancy, major cardiac care and heavy immunosuppression override every stack preference on this page.
See how DSIP fits your week
The injection scheduler spaces doses using the clinical timing data, flags the pairs above before you draw them, and tells you why.
Model this in the injection schedulerThe studies
Human trials: No completed human efficacy trial that establishes a dose for the use people are chasing.
Open questions: Treat published dosing as observed practice, not a validated protocol.
Published papers
Indexed from Europe PMC and refreshed weekly. Each link opens the paper itself.
- Efficient Scheduling of Heterogeneous Messages in the FlexRay Dynamic Segment
Sensors (Basel) · 2026. Li M, Liu S, Sun H, Zhang K, Xu Y.
- Therapeutic Peptides in Aesthetic, Metabolic and Endocrine Conditions: Effects, Safety, Clinical Applications, and Future Perspectives
Int J Mol Sci · 2026 · Review. Renke G, Chinellato L.
- Ion-Pair Speciation in Aqueous Alkali Fluorides from Nuclear Magnetic Resonance of <sup>19</sup>F
J Phys Chem B · 2026. Musiał M, Miller S, Suiter CL, Klem H, Paulechka E, Schwarz KA, Widegren J, Riccardi D.
- Predicting Sanitation Behaviors: Comparison of Willingness to Pay Techniques for Sanitation Services in Urban Dhaka, Bangladesh
Environ Health Insights · 2026. Alam MU, Tabassum KF, Hosen I, Laabar TD, Norman R, Li IW.
- Peptide-Based Approaches for Pain Relief and Healing in Wounds
Int J Mol Sci · 2026 · Review. Kołodyńska K, Kamysz W, Kleczkowska P.
- Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions
J Am Acad Orthop Surg Glob Res Rev · 2026 · Review. Rahman OF, Lee SJ, Seeds WA.
- Equity and Social Care in Medicaid through Community Care Hubs
Am J Law Med · 2025. Jacobi JV.
- Discovery of first-in-class inhibitors of the TRF1:TIN2 protein:protein interaction by fragment screening
Sci Rep · 2025. Casale G, Liu M, Le Bihan YV, Inian O, Stammers E, Caldwell J, van Montfort RLM, Collins I, Guettler S.
- Enantioselective and Diastereoselective Synthesis of Azaspiro[n.2]alkanes by Rhodium-Catalyzed Cyclopropanations
ACS Catal · 2025. Sailer JK, Ly D, Wang A, Musaev DG, Davies HML.
- Crossing Barriers: Advancements in Macromolecular Therapeutics for Neurodegenerative Diseases and Strategies to Overcome the Blood-Brain Barrier
ACS Pharmacol Transl Sci · 2025 · Review. Alo B, Lamers C.
Search the full literature
- PubMed: all indexed papers
Every indexed paper, newest first. Filter to Clinical Trial or Review in the sidebar.
- PubMed: human clinical trials only
The honest test of an evidence claim. An empty result is itself an answer.
- ClinicalTrials.gov registrations
Registered, ongoing and completed trials, including ones that never published.
- Europe PMC full text
Often surfaces open-access full text that PubMed only abstracts.